Mathieu Hénault
PhD Student / Yeast ecological genomics
e-mail: mathieu.henault.1 [at] ulaval.ca
Biography
I am from the region of Bas-Saint-Laurent (Quebec, Canada) where I did most of my pre-university education. I then completed a bachelor’s in Biochemistry at Université Laval in 2017. During my bachelor’s degree I had the opportunity to work in Christian’s lab as an intern, following which I caught the academic research bug. I have now been a PhD student in Biochemistry since September 2017.
Research interests
I mostly focus on evolutionary genomics and more specifically on the evolution of eukaryotic genome architecture and on the close relationship between mitochondrial and nuclear genomes. I am using the wild yeast Saccharomyces paradoxus and related species as well as experimental and bioinformatics tools like experimental evolution and nanopore whole-genome sequencing.
Publications
Hénault M, Marsit S, Charron G & Landry CR. The genomic landscape of transposable elements in yeast hybrids is shaped by structural variation and genotype-specific modulation of transposition rates. eLife, 12:RP89277 (2023)
Hénault M, Marsit S, Charron G & Landry CR. Hybridization drives mitochondrial DNA degeneration and metabolic shift in a species with biparental mitochondrial inheritance. Genome Res, gr.276885.122 (2022)
Marsit S, Hénault M, Charron G, Fijarczyk A, & Landry CR. The neutral rate of whole-genome duplication varies among yeast species and their hybrids. Nature Communications 12, 3126 (2021)
Hénault M. The challenges of predicting transposable element activity in hybrids. Current Genetics, 1-6 (2021)
Hénault M, Marsit S, Charron G & Landry CR. The effect of hybridization on transposable element accumulation in an undomesticated fungal species. eLife 9, e60474 (2020)
Fijarczyk A, Hénault M, Marsit S, Charron G, Fischborn T, Nicole-Labrie L, & Landry CR. The genome sequence of the Jean-Talon strain, an archeological tetraploid beer yeast from Québec. G3: Genes, Genomes, Genetics 10 (9), 3087-3097 (2020)
Hallin J, Cisneros AF, Hénault M, Fijarczyk A, Dandage R, Bautista C, & Landry CR. Similarities in biological processes can be used to bridge ecology and molecular biology. Evolutionary Applications 13 (6), 1335-1350 (2020)
Charron G*, Marsit S*, Hénault M, Martin H, & Landry CR. Spontaneous whole-genome duplication restores fertility in interspecific hybrids. Nature Communications 10 (1), 1-10 (2019)
Eberlein C*, Hénault M*, Fijarczyk A, Charron G, Bouvier M, Kohn LM, Anderson JB, & Landry CR. Hybridization is a recurrent evolutionary stimulus in wild yeast speciation. Nature Communications 10 (1), 1-14 (2019)
Hénault M*, Eberlein C*, Charron G, Durand E, Nielly-Thibault L, Martin H & Landry CR, Yeast population genomics goes wild: the case of Saccharomyces paradoxus. In: Polz M, Rajora OP (eds) Population genomics: microorganisms. Springer, Cham (2017)
Leducq JB*, Henault M*, Charron G, Nielly-Thibault L, Terrat Y, Fiumera HL, Shapiro BJ & Landry CR, Mitochondrial recombination and introgression during speciation by hybridization. Molecular Biology and Evolution 34:1947-1959 (2017)
Hénault M & CR Landry. When nuclear-encoded proteins and mitochondrial RNAs do not get along, species split apart. EMBO Reports 18:8–10 (2017)